Evaluation of Medonic M51 hematology system

Typically, hematology analyses are performed in large clinical core laboratories. However, there are circumstances, under which near-patient monitoring of blood cell counts can be essential. Independent of clinical setup, accuracy and precision of the clinical analyses are of equal importance.

Medonic M51 – explore your possibilities

Medonic M51 is a hematology system intended for the smaller laboratory (Fig 1). The analyzer provides information on 29 parameters for the CBC, including white blood cell (WBC), red blood cell (RBC) and platelet (PLT) counts as well as a 5-part differential count of the WBCs.

Medonic M51 employs well-proven measurement technologies. The analyzer uses impedance for RBC and PLT counts, while the WBC differential is conducted by laser-based flow cytometry. Hemoglobin (HGB) is determined spectrophotometrically.

Medonic M51 5-part hematology analyzer

Fig 1. Medonic M51 is a 5-part hematology analyzer intended for the cost-minded clinical laboratory. The user-friendly design makes system operations easy. Robust software and hardware components ensure a reliable system performance. With its small footprint, Medonic M51 is well suited for the typical physician office laboratory.

Medonic M51 provides comparable performance to reference system

Dr. S.P. Ganesan and coworkers at the Hitech Diagnostic Centre (HDC) in Chennai, India conducted a study to compare the performance of Medonic M51 with a reference system intended for the larger hospital laboratory (Fig 2).

”Medonic M51 is an entry-level hematology system intended for the smaller laboratory. The work conducted in collaboration between Boule Diagnostics and Hitech Diagnostic Centre (HDC) in Chennai, India compares the performance of Medonic M51 with the XN-1000 reference hematology system (Sysmex Corp.) intended for the large clinical laboratory”, Dr. Ganesan explains. “The results show that Medonic M51 is in good agreement with the reference system. The analyzers provide similar conditions for patient decisions. Medonic M51 generated analytical data close to microscopic examination and is a good option for the smaller clinical and hospital laboratories.”
Fig 2. Agreement between cell count in the Medonic M51 test and XN-1000 reference (Sysmex Corp.) hematology analyzers. Passing-Bablok regression graphs are shown for (A) WBC, (B) RBC, (C) HGB, (D) MCV, (E) HCT, (F) RDW%, (G) PLT, and (H) MPV. In regression plots, the gray line is the line of identity (x = y) and the red line is the line of best fit.

Fig 2. Agreement between cell count in the Medonic M51 test and XN-1000 reference (Sysmex Corp.) hematology analyzers. Passing-Bablok regression graphs are shown for (A) WBC, (B) RBC, (C) HGB, (D) MCV, (E) HCT, (F) RDW%, (G) PLT, and (H) MPV. In regression plots, the gray line is the line of identity (x = y) and the red line is the line of best fit.

Learn more

Read the full application note that the describes the Evaluation of the performance of Medonic M51 in comparison with a reference system